The completion of the Human Genome Project and the development of high-throughput
polymorphism identification methods have allowed researchers to carry out full genetic
analyses of many clinically relevant genes. However, few studies have combined genetic
analysis with in vitro phenotyping to better understand the relationship between genetic
variation and protein function. Many transporters in the kidney are thought to play key roles
in defense against a variety of foreign substances. The goal of this study was to understand …