Immunoregulatory mechanisms involved in elicitation of allergic contact hypersensitivity

S Grabbe, T Schwarz - Immunology today, 1998 - cell.com
S Grabbe, T Schwarz
Immunology today, 1998cell.com
Although the pathophysiology of contact hypersensitivity (CHS) might appear to be well
understood, this only applies to the sensitization phase. Little is known about the elicitation
phase, and fundamental differences exist between CHS and other forms of delayed-type
hypersensitivity responses. Here, Stephan Grabbe and Thomas Schwarz summarize the
role of different cellular components and soluble mediators in the inflammatory tissue
response during CHS elicitation.
Abstract
Although the pathophysiology of contact hypersensitivity (CHS) might appear to be well understood, this only applies to the sensitization phase. Little is known about the elicitation phase, and fundamental differences exist between CHS and other forms of delayed-type hypersensitivity responses. Here, Stephan Grabbe and Thomas Schwarz summarize the role of different cellular components and soluble mediators in the inflammatory tissue response during CHS elicitation.
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