Cell signaling plays a key role in the development of all multicellular organisms. Numerous
studies have established the importance of Hedgehog signaling in a wide variety of
regulatory functions during the development of vertebrate and invertebrate organisms.
Several reviews have discussed the signaling components in this pathway, their various
interactions, and some of the general principles that govern Hedgehog signaling
mechanisms. This review focuses on the developing systems themselves, providing a …