[HTML][HTML] Cholecystokinin activates PYK2/CAKβ by a phospholipase C-dependent mechanism and its association with the mitogen-activated protein kinase signaling …
PYK2/CAKβ is a recently described cytoplasmic tyrosine kinase related to p125 focal
adhesion kinase (p125 FAK) that can be activated by a number of stimuli including growth
factors, lipids, and some G protein-coupled receptors. Studies suggest PYK2/CAKβ may be
important for coupling various G protein-coupled receptors to the mitogen-activated protein
kinase (MAPK) cascade. The hormone neurotransmitter cholecystokinin (CCK) is known to
activate both phospholipase C-dependent cascades and MAPK signaling pathways; …
adhesion kinase (p125 FAK) that can be activated by a number of stimuli including growth
factors, lipids, and some G protein-coupled receptors. Studies suggest PYK2/CAKβ may be
important for coupling various G protein-coupled receptors to the mitogen-activated protein
kinase (MAPK) cascade. The hormone neurotransmitter cholecystokinin (CCK) is known to
activate both phospholipase C-dependent cascades and MAPK signaling pathways; …