[HTML][HTML] Role of adiponectin in preventing vascular stenosis: the missing link of adipo-vascular axis
M Matsuda, I Shimomura, M Sata, Y Arita… - Journal of Biological …, 2002 - ASBMB
Obesity is more linked to vascular disease, including atherosclerosis and restenotic change,
after balloon angioplasty. The precise mechanism linking obesity and vascular disease is
still unclear. Previously we have demonstrated that the plasma levels of adiponectin, an
adipose-derived hormone, decreases in obese subjects, and that hypoadiponectinemia is
associated to ischemic heart disease. In current the study, we investigated the in vivorole of
adiponectin on the neointimal thickening after artery injury using adiponectin-deficient mice …
after balloon angioplasty. The precise mechanism linking obesity and vascular disease is
still unclear. Previously we have demonstrated that the plasma levels of adiponectin, an
adipose-derived hormone, decreases in obese subjects, and that hypoadiponectinemia is
associated to ischemic heart disease. In current the study, we investigated the in vivorole of
adiponectin on the neointimal thickening after artery injury using adiponectin-deficient mice …