An emergency response team for membrane repair
PL McNeil, T Kirchhausen - Nature reviews Molecular cell biology, 2005 - nature.com
PL McNeil, T Kirchhausen
Nature reviews Molecular cell biology, 2005•nature.comAbstract On demand, rapid Ca2+-triggered homotypic and exocytic membrane-fusion events
are required to repair a torn plasma membrane, and we propose that this emergency-based
fusion differs fundamentally from other rapid, triggered fusion reactions. Emergency fusion
might use a specialized protein and organelle emergency response team that can
simultaneously promote impromptu homotypic fusion events between organelles and
exocytic fusion events along the vertices between these fusion products and the plasma …
are required to repair a torn plasma membrane, and we propose that this emergency-based
fusion differs fundamentally from other rapid, triggered fusion reactions. Emergency fusion
might use a specialized protein and organelle emergency response team that can
simultaneously promote impromptu homotypic fusion events between organelles and
exocytic fusion events along the vertices between these fusion products and the plasma …
Abstract
On demand, rapid Ca2+-triggered homotypic and exocytic membrane-fusion events are required to repair a torn plasma membrane, and we propose that this emergency-based fusion differs fundamentally from other rapid, triggered fusion reactions. Emergency fusion might use a specialized protein and organelle emergency response team that can simultaneously promote impromptu homotypic fusion events between organelles and exocytic fusion events along the vertices between these fusion products and the plasma membrane.
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