Synthetic peptides corresponding to keratin subunits elicit highly specific antibodies.
DR Roop, CK Cheng, L Titterington, CA Meyers… - Journal of Biological …, 1984 - ASBMB
The presence of common antigenic determinants within all keratin proteins has made
difficult the production of antisera which are monospecific for individual keratin subunits.
Synthetic peptides corresponding to the carboxyl-terminal amino acid sequences of the
mouse 59-and 67-kilodalton keratins were used to produce antibodies which were highly
specific for these keratin subunits. This method of antibody production was chosen after
examination of amino acid sequence data (which were deduced from the nucleotide …
difficult the production of antisera which are monospecific for individual keratin subunits.
Synthetic peptides corresponding to the carboxyl-terminal amino acid sequences of the
mouse 59-and 67-kilodalton keratins were used to produce antibodies which were highly
specific for these keratin subunits. This method of antibody production was chosen after
examination of amino acid sequence data (which were deduced from the nucleotide …