High level of androgen receptor is associated with aggressive clinicopathologic features and decreased biochemical recurrence-free survival in prostate: cancer …
R Li, T Wheeler, H Dai, A Frolov… - The American journal …, 2004 - journals.lww.com
Background: Prostate cancer (PCa) is androgen dependent and is regulated by
androgen/androgen receptor (AR) signaling pathway. However, the clinical significance of
AR is in question. In this regard, we have correlated levels of AR expression with some well-
established clinical and pathologic parameters and assessed the prognostic value of AR
expression in PCa patients treated with radical prostatectomy. Design: A total of 640 cases
treated with radical prostatectomy were used to build tissue microarrays. Normal prostate …
androgen/androgen receptor (AR) signaling pathway. However, the clinical significance of
AR is in question. In this regard, we have correlated levels of AR expression with some well-
established clinical and pathologic parameters and assessed the prognostic value of AR
expression in PCa patients treated with radical prostatectomy. Design: A total of 640 cases
treated with radical prostatectomy were used to build tissue microarrays. Normal prostate …