Protein C anticoagulant pathway and its role in controlling microvascular thrombosis and inflammation

CT Esmon - Critical care medicine, 2001 - journals.lww.com
Objective To review the physiologic and biochemical mechanisms that suggest that protein
C and activated protein C (APC) have unique properties that make them good candidates for
the treatment of microvascular thrombosis, disseminated intravascular coagulation, and
sepsis.