High frequency of open-angle glaucoma in Japanese patients with Alzheimer's disease
H Tamura, H Kawakami, T Kanamoto, T Kato… - Journal of the …, 2006 - Elsevier
The clinical and genetic relationships between Alzheimer's disease (AD) and glaucoma
remain obscure. The aim of this study was to determine the prevalence of open-angle
glaucoma (OAG) in patients with AD and whether the apolipoprotein E (APOE) 4 allele is
associated with AD, with or without OAG, in Japanese. The groups consisted of 172 patients
with the diagnostic criteria of AD and 176 age-matched controls. Ophthalmic examinations
were conducted, and genomic analysis was performed by PCR and digestion of products …
remain obscure. The aim of this study was to determine the prevalence of open-angle
glaucoma (OAG) in patients with AD and whether the apolipoprotein E (APOE) 4 allele is
associated with AD, with or without OAG, in Japanese. The groups consisted of 172 patients
with the diagnostic criteria of AD and 176 age-matched controls. Ophthalmic examinations
were conducted, and genomic analysis was performed by PCR and digestion of products …