Can sustained weight loss in overweight individuals reduce the risk of diabetes mellitus?

LL Moore, AJ Visioni, PWF Wilson, RB D'Agostino… - …, 2000 - journals.lww.com
Although rates of adult-onset diabetes mellitus increase with increasing obesity, there is little
evidence that weight loss in overweight individuals can reduce their risk of developing
diabetes. Using data from the Framingham Study, we examined the effects of sustained and
nonsustained weight loss on risk of diabetes mellitus among 618 overweight (body mass
index≥ 27) subjects 30–50 years of age. To separate sustained from nonsustained weight
loss, we examined weight change in two consecutive 8-year periods. Subjects who had …