[HTML][HTML] Cell cholesterol efflux: integration of old and new observations provides new insights
GH Rothblat, M de la Llera-Moya, V Atger… - Journal of lipid …, 1999 - ASBMB
Numerous studies using a variety of cell/acceptor combinations have demonstrated
differences in cholesterol efflux among cells. These studies also show that different
acceptors, ranging from simple molecules like cyclodextrins to serum, stimulate efflux
through a variety of mechanisms. By combining early observations with data derived from
recent studies, it is now possible to formulate a model for cell cholesterol efflux which
proposes that an array of different mechanisms, including aqueous diffusion, lipid-free …
differences in cholesterol efflux among cells. These studies also show that different
acceptors, ranging from simple molecules like cyclodextrins to serum, stimulate efflux
through a variety of mechanisms. By combining early observations with data derived from
recent studies, it is now possible to formulate a model for cell cholesterol efflux which
proposes that an array of different mechanisms, including aqueous diffusion, lipid-free …