Hair follicle structures targeted by antibodies in patients with alopecia areata
DJ Tobin, SK Hann, MS Song… - Archives of …, 1997 - jamanetwork.com
Objective: To identify the structures in hair follicles (HFs) targeted by alopecia areata (AA)
antibodies and the role of antigen expression in the development or localization of AA
lesions. Design: The identity of HF structures targeted by AA antibodies was determined by
indirect immunofluorescence and the level of antigen expression from the intensity of the
staining. Setting: A university medical center. Patients: Ten patients with active AA and 8
control individuals. Results: Antibodies to anagen HFs were present in up to 90% of patients …
antibodies and the role of antigen expression in the development or localization of AA
lesions. Design: The identity of HF structures targeted by AA antibodies was determined by
indirect immunofluorescence and the level of antigen expression from the intensity of the
staining. Setting: A university medical center. Patients: Ten patients with active AA and 8
control individuals. Results: Antibodies to anagen HFs were present in up to 90% of patients …