Epithelial Ca2+ and Mg2+ channels in health and disease
JGJ Hoenderop, RJM Bindels - Journal of the American Society of …, 2005 - journals.lww.com
A near constancy of the extracellular Ca 2+ and Mg 2+ concentration is required for
numerous physiologic functions at the organ, tissue, and cellular levels. This suggests that
minor changes in the extracellular concentration of these divalents must be detected to allow
the appropriate correction by the homeostatic systems. The maintenance of the Ca 2+ and
Mg 2+ balance is controlled by the concerted action of intestinal absorption, renal excretion,
and exchange with bone. After years of research, rapid progress was made recently in …
numerous physiologic functions at the organ, tissue, and cellular levels. This suggests that
minor changes in the extracellular concentration of these divalents must be detected to allow
the appropriate correction by the homeostatic systems. The maintenance of the Ca 2+ and
Mg 2+ balance is controlled by the concerted action of intestinal absorption, renal excretion,
and exchange with bone. After years of research, rapid progress was made recently in …