Relationship of oncogenes (sFas, Bcl-2) and cytokines (IL-10, alfa-TNF) with the activity of systemic lupus erythematosus.
C Miret, J Font, R Molina, M Garcia-Carrasco… - Anticancer …, 2001 - europepmc.org
C Miret, J Font, R Molina, M Garcia-Carrasco, X Filella, M Ramos, R Cervera, A Ballesta…
Anticancer research, 2001•europepmc.orgBackground Different oncogenes (Fas and bcl-2) and diverse cytokines (IL-10 and alfa-TNF)
may have an effect on the regulation of apoptosis. The majority of studies to date have
evaluated only one or two of these elements independently and it is difficult to obtain a
global view of apoptosis disregulation in the pathogenesis of systemic lupus erythematosus
(SLE) and their role in disease activity. The aim of this study was to evaluate serum levels of
sFas, bcl-2, IL-10 and alfa-TNF in human SLE patients and to analyze their relationship with …
may have an effect on the regulation of apoptosis. The majority of studies to date have
evaluated only one or two of these elements independently and it is difficult to obtain a
global view of apoptosis disregulation in the pathogenesis of systemic lupus erythematosus
(SLE) and their role in disease activity. The aim of this study was to evaluate serum levels of
sFas, bcl-2, IL-10 and alfa-TNF in human SLE patients and to analyze their relationship with …
Background
Different oncogenes (Fas and bcl-2) and diverse cytokines (IL-10 and alfa-TNF) may have an effect on the regulation of apoptosis. The majority of studies to date have evaluated only one or two of these elements independently and it is difficult to obtain a global view of apoptosis disregulation in the pathogenesis of systemic lupus erythematosus (SLE) and their role in disease activity. The aim of this study was to evaluate serum levels of sFas, bcl-2, IL-10 and alfa-TNF in human SLE patients and to analyze their relationship with disease activity and with regulation of the apoptotic process.
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