Pharmacologic elevation of high-density lipoproteins: recent insights on mechanism of action and atherosclerosis protection
CD Meyers, ML Kashyap - Current Opinion in Cardiology, 2004 - journals.lww.com
CD Meyers, ML Kashyap
Current Opinion in Cardiology, 2004•journals.lww.comAn understanding of the atheroprotective mechanisms of HDL is essential for the rational
use of currently available drugs and directed development of new drugs. Increasing total
HDL cholesterol may not be as important as increasing the functional properties of HDL.
Cardiovascular disease treatment and prevention can be improved by combining current
low-density lipoprotein-based strategies with effective HDL-based interventions.
use of currently available drugs and directed development of new drugs. Increasing total
HDL cholesterol may not be as important as increasing the functional properties of HDL.
Cardiovascular disease treatment and prevention can be improved by combining current
low-density lipoprotein-based strategies with effective HDL-based interventions.
Summary
An understanding of the atheroprotective mechanisms of HDL is essential for the rational use of currently available drugs and directed development of new drugs. Increasing total HDL cholesterol may not be as important as increasing the functional properties of HDL. Cardiovascular disease treatment and prevention can be improved by combining current low-density lipoprotein-based strategies with effective HDL-based interventions.
Lippincott Williams & Wilkins