Comparative efficacy of acellular pertussis vaccines: an analysis of recent trials

JD Cherry - The Pediatric infectious disease journal, 1997 - journals.lww.com
JD Cherry
The Pediatric infectious disease journal, 1997journals.lww.com
Diphtheria-tetanus-acellular pertussis vaccines have been licensed in the United States
since 1991. Compared with the whole cell pertussis component diphtheria-tetanus-pertussis
vaccine, the diphtheria-tetanus-acellular pertussis vaccines were found in reactogenicity
and immunogenicity studies to be immunogenic with respect to their specific antigen content
and to be associated with less severe and less frequent adverse reactions.
Abstract
Diphtheria-tetanus-acellular pertussis vaccines have been licensed in the United States since 1991. Compared with the whole cell pertussis component diphtheria-tetanus-pertussis vaccine, the diphtheria-tetanus-acellular pertussis vaccines were found in reactogenicity and immunogenicity studies to be immunogenic with respect to their specific antigen content and to be associated with less severe and less frequent adverse reactions.
Lippincott Williams & Wilkins