[HTML][HTML] Energy metabolism after 2 y of energy restriction: the biosphere 2 experiment

C Weyer, RL Walford, IT Harper, M Milner… - The American journal of …, 2000 - Elsevier
Background: An adaptive decrease in energy expenditure (EE) in response to 6 mo of
severely restricted energy intake was shown in a classic semistarvation study—the
Minnesota experiment. Objective: Our objective was to examine whether such adaptation
also occurs in response to less severe but sustained energy restriction. Design: Body
composition, 1-wk total EE (TEE), 24-h sedentary EE, and spontaneous physical activity
were measured in 8 healthy subjects (4 men and 4 women) at the end of a 2-y confinement …