The role of leptin in the control of body weight
RL Leibel - Nutrition reviews, 2002 - academic.oup.com
RL Leibel
Nutrition reviews, 2002•academic.oup.comThe Role of Leptin in the Control of Body Weight Page 1 October 2002: (II)S15–S19 The Role
of Leptin in the Control of Body Weight Rudolph L. Leibel, MD Physiologic responses to high
and low leptin concentrations are strikingly asymmetrical. High concentrations often produce
minimal effects, whereas low concentrations provoke strong counterregulatory responses. A
model and rationale for the physiology is presented. Key Words: leptin concentrations,
counterregulatory responses, energy balance, weight, obesity © 2002 International Life …
of Leptin in the Control of Body Weight Rudolph L. Leibel, MD Physiologic responses to high
and low leptin concentrations are strikingly asymmetrical. High concentrations often produce
minimal effects, whereas low concentrations provoke strong counterregulatory responses. A
model and rationale for the physiology is presented. Key Words: leptin concentrations,
counterregulatory responses, energy balance, weight, obesity © 2002 International Life …
Abstract
Physiologic responses to high and low leptin concentrations are strikingly asymmetrical. High concentrations often produce minimal effects, whereas low concentrations provoke strong counterregulatory responses. A model and rationale for the physiology is presented.
Oxford University Press