Development and function of CD25+ CD4+ regulatory T cells
Z Fehérvari, S Sakaguchi - Current opinion in immunology, 2004 - Elsevier
Z Fehérvari, S Sakaguchi
Current opinion in immunology, 2004•ElsevierThe essential role played by CD25+ CD4+ regulatory T cells (TR cells) in the control of
physiological as well as pathological immunity is now well established, but many aspects of
their biology still remain unclear. One of the unresolved issues regards their development:
where does this occur, what signals are required, and how do TR cells fit into the larger
taxonomy of the T-cell family? Recent data has begun to shed light on the development and
function of these important cells.
physiological as well as pathological immunity is now well established, but many aspects of
their biology still remain unclear. One of the unresolved issues regards their development:
where does this occur, what signals are required, and how do TR cells fit into the larger
taxonomy of the T-cell family? Recent data has begun to shed light on the development and
function of these important cells.
The essential role played by CD25+CD4+ regulatory T cells (TR cells) in the control of physiological as well as pathological immunity is now well established, but many aspects of their biology still remain unclear. One of the unresolved issues regards their development: where does this occur, what signals are required, and how do TR cells fit into the larger taxonomy of the T-cell family? Recent data has begun to shed light on the development and function of these important cells.
Elsevier