Signal sorting by G-protein-linked receptors

G Milligan - Advances in Pharmacology, 1995 - Elsevier
Publisher Summary The vast range of individual gene products encoding G-protein-linked
receptors and the fact that individual neurotransmitters and hormones have, in many cases,
the potential to activate multiple receptor subtypes provide the potential for exquisite control
of the sensitivity of cellular response to these agents. Such hormone and neurotransmitter-
encoded signals arriving at a cell are perceived and sorted to maintain specificity of the
signal and to prevent misinterpretation of the perceived signal. This chapter focuses on how …