Therapy of pemphigus
GG Tóth, MF Jonkman - Clinics in dermatology, 2001 - cidjournal.com
Pemphigus is a severe chronic autoimmune blis-tering disease of skin and mucous
membranes that was lethal until 1950s when glucocorticoids became available.
Glucocorticoids are the cornerstone of treatment. The disease, however, is still difficult to
treat, and the long-term use of steroids leads to severe side-effects. Pemphigus is a rare
disease with an annual incidence of approximately 0.1 to 0.42 per 100,000. 1–3 A peak
incidence occurs in patients between the fourth and sixth decade. About 0.8% of all …
membranes that was lethal until 1950s when glucocorticoids became available.
Glucocorticoids are the cornerstone of treatment. The disease, however, is still difficult to
treat, and the long-term use of steroids leads to severe side-effects. Pemphigus is a rare
disease with an annual incidence of approximately 0.1 to 0.42 per 100,000. 1–3 A peak
incidence occurs in patients between the fourth and sixth decade. About 0.8% of all …