[PDF][PDF] Centre d'etude du polymorphisme humain (CEPH): collaborative genetic mapping of the human genome

J Dausset, H Cann, D Cohen, M Lathrop, JM Lalouel… - Genomics, 1990 - academia.edu
J Dausset, H Cann, D Cohen, M Lathrop, JM Lalouel, R White
Genomics, 1990academia.edu
Elsewhere in this issue of Genomics is the first consortium map, that of chromosome 10, from
the CEPH collabaration to map the human genome genetically. The map is truIy a
collaborative achievement, in that the underlying genotypes represent the efforts of
laboratories collaborating with each other and with CEPH to produce a primary genetic map
of the gename, consisting ofpolymorphic markers placed at approximately ZO-CM intervals
along each of the human autosomea and the X chromosome. Such a map provides a tool for …
Elsewhere in this issue of Genomics is the first consortium map, that of chromosome 10, from the CEPH collabaration to map the human genome genetically. The map is truIy a collaborative achievement, in that the underlying genotypes represent the efforts of laboratories collaborating with each other and with CEPH to produce a primary genetic map of the gename, consisting ofpolymorphic markers placed at approximately ZO-CM intervals along each of the human autosomea and the X chromosome. Such a map provides a tool for the systematic localization of genes that determine inherited diseases and of other genes of interest. Genetic Iocalization can be the first step in the development of diagnoetic tests and isolation of a disease-determining gene. The purpose of this program descsiption is to provide information about CEPH and the basis and nature of the collaboration.
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