[HTML][HTML] Gas6 receptors Axl, Sky and Mer enhance platelet activation and regulate thrombotic responses

WR Gould, SM Baxi, R Schroeder, YW Peng… - Journal of Thrombosis …, 2005 - Elsevier
Gas6 (encoded by growth arrest‐specific gene 6) is a vitamin‐K dependent protein highly
homologous to coagulation protein S that is secreted from platelet α‐granules and has
recently been demonstrated to participate in platelet thrombus formation. The current study
evaluated the contribution of each of the three known Gas6 receptors (Axl, Sky and Mer) in
human and mouse platelet function. Flow cytometry analyses confirmed that all three
receptors are present on both human and mouse platelets. Pre‐incubation of human …