[HTML][HTML] A conserved sequence motif in the integrin β3 cytoplasmic domain is required for its specific interaction with β3-endonexin
M Eigenthaler, L Höfferer, SJ Shattil… - Journal of Biological …, 1997 - ASBMB
Integrin signaling is mediated by interaction of integrin cytoplasmic domains with
intracellular signaling molecules. Recently, we identified a novel 111-amino acid
polypeptide, termed β 3-endonexin, which interacts selectively with the integrin β 3
cytoplasmic domain. In the present study we conducted a systematic mutational analysis of
both the integrin β 3 cytoplasmic domain and β 3-endonexin to map sites required for
interaction. The interaction of the full-length β 3 integrin subunit with β 3-endonexin in vitro …
intracellular signaling molecules. Recently, we identified a novel 111-amino acid
polypeptide, termed β 3-endonexin, which interacts selectively with the integrin β 3
cytoplasmic domain. In the present study we conducted a systematic mutational analysis of
both the integrin β 3 cytoplasmic domain and β 3-endonexin to map sites required for
interaction. The interaction of the full-length β 3 integrin subunit with β 3-endonexin in vitro …