The relationship among serum insulin-like growth factor-I, insulin-like growth factor-I gene polymorphism, and bone mineral density in postmenopausal women in …

JG Kim, KR Roh, JY Lee - American journal of obstetrics and gynecology, 2002 - Elsevier
OBJECTIVE: The objective of this study was to test the hypothesis that the cytosine-adenine
polymorphism in the insulin-like growth factor-I gene is associated with serum insulin-like
growth factor-I levels and bone mineral density. STUDY DESIGN: The insulin-like growth
factor-I cytosine-adenine polymorphism was analyzed in 300 postmenopausal Korean
women. Serum insulin-like growth factor-I, bone alkaline phosphatase, and carboxy-terminal
cross-linking telopeptide of type I collagen were measured by immunoradiometric assay and …