Melanoma cell lines from different stages of progression and their biological and molecular analyses
K Satyamoorthy, E DeJesus, AJ Linnenbach… - Melanoma …, 1997 - journals.lww.com
The biological and molecular characteristics of cell lines from metastatic melanomas have
been extensively studied but less is known about cells from the biologically earliest stage of
primary melanoma. The overall success rate of establishing permanent cell lines from such
lesions is only 10% of that for biologically late primary or metastatic melanomas, although
our laboratory now has eight cell lines available. The cells are immortal but show reduced or
no proliferation in soft agar and immunodeficient mice when compared with primary …
been extensively studied but less is known about cells from the biologically earliest stage of
primary melanoma. The overall success rate of establishing permanent cell lines from such
lesions is only 10% of that for biologically late primary or metastatic melanomas, although
our laboratory now has eight cell lines available. The cells are immortal but show reduced or
no proliferation in soft agar and immunodeficient mice when compared with primary …