Oral and genital ulceration: a unique presentation of immunodeficiency in Athabascan-speaking American Indian children with severe combined immunodeficiency

PC Kwong, AS O'Marcaigh, R Howard… - Archives of …, 1999 - jamanetwork.com
Background Oral and genital ulcerations have been previously reported in 3 Navajo children
diagnosed with severe combined immunodeficiency disease with T-and B-cell lymphopenia
(T− B−–SCID). Objective To evaluate the occurrence of oral and genital ulcerations in 12
Athabascan-speaking American Indians with a diagnosis of T− B−–SCID (SCIDA group) and
to compare their occurrence in non–Athabascan-speaking children with SCID (control
group). We also observed the course of these ulcerations in response to bone marrow …