Transcription of the human neuronal nitric oxide synthase gene in the central nervous system is mediated by multiple promoters
AP Young, F Murad, H Vaessin, J Xie, TK Rife - Advances in pharmacology, 1995 - Elsevier
Publisher Summary The principal contribution described in this chapter is the identification
and initial characterization of two distinct promoters for human NOS1 gene transcription.
Although closely linked, these promoters are separable, in that they can independently drive
the expression of appropriately linked reporter genes in transfection systems. The
demonstration of independent promoter activities renders it unlikely that alternative splicing
of a single primary transcript produces the heterogeneity in NOS1 mRNA structure reflected …
and initial characterization of two distinct promoters for human NOS1 gene transcription.
Although closely linked, these promoters are separable, in that they can independently drive
the expression of appropriately linked reporter genes in transfection systems. The
demonstration of independent promoter activities renders it unlikely that alternative splicing
of a single primary transcript produces the heterogeneity in NOS1 mRNA structure reflected …