Biphasic effects of anandamide

E Sulcova, R Mechoulam, E Fride - Pharmacology Biochemistry and …, 1998 - Elsevier
Effects of the endogenous cannabimimetic anandamide were assessed over a wide dose
range in a series of physiological and behavioral assays. These included the tetrad of tests
in mice commonly used to assess cannabinoid-induced effects (motor activity, ring
catalepsy, hypothermia, and analgesia tests), as well as a model for agonistic behavior on
dyadic interactions of singly housed males with nonaggressive group-housed partners.
Anandamide-induced effects on leukocyte phagocytosis were measured in a …