NKT cells: facts, functions and fallacies
DI Godfrey, KJL Hammond, LD Poulton, MJ Smyth… - Immunology today, 2000 - cell.com
The proposed roles of NK1. 1+ T (NKT) cells in immune responses range from suppression
of autoimmunity to tumor rejection. Heterogeneity of these cells contributes to the
controversy surrounding their development and function. This review aims to provide an
update on NKT cell biology and, whenever possible, to compare what is known about NKT-
cell subsets.
of autoimmunity to tumor rejection. Heterogeneity of these cells contributes to the
controversy surrounding their development and function. This review aims to provide an
update on NKT cell biology and, whenever possible, to compare what is known about NKT-
cell subsets.
Abstract
The proposed roles of NK1.1+ T (NKT) cells in immune responses range from suppression of autoimmunity to tumor rejection. Heterogeneity of these cells contributes to the controversy surrounding their development and function. This review aims to provide an update on NKT cell biology and, whenever possible, to compare what is known about NKT-cell subsets.
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