Circulating levels of granulocyte macrophage colony-stimulating factor in patients with the systemic inflammatory response syndrome
D Torre, R Tambini, M Manfredi, V Mangani, P Livi… - Journal of Infection, 2003 - Elsevier
Objectives. Granulocyte-macrophage colony stimulating factor (GM-CSF) is a key regulator
cytokine that modulates the proliferation and maturation of polymorphonuclear and
mononuclear progenitors. This study was designed to investigate and clarify the role of GM-
CSF in 52 critically ill patients with systemic inflammatory response syndrome (SIRS).
Methods. Serum levels of GM-CSF were detected by an immunoenzyme assay. Results. Our
results clearly show that the serum concentrations of GM-CSF were significantly elevated in …
cytokine that modulates the proliferation and maturation of polymorphonuclear and
mononuclear progenitors. This study was designed to investigate and clarify the role of GM-
CSF in 52 critically ill patients with systemic inflammatory response syndrome (SIRS).
Methods. Serum levels of GM-CSF were detected by an immunoenzyme assay. Results. Our
results clearly show that the serum concentrations of GM-CSF were significantly elevated in …