Primary immunodeficiency diseases: an update
L Notarangelo, JL Casanova, A Fischer, J Puck… - Journal of Allergy and …, 2004 - Elsevier
Although relatively rare, primary immune deficiency diseases (PIDs) provide an excellent
window into the functioning of the immune system. In the late 1960s, observations on these
diseases, with their associated infections and genetics, bisected the immune system into
humoral immunity and cell-mediated immunity. These diseases also represent a challenge
in their diagnosis and treatment. Beginning in 1970, a unified nomenclature for the then-
known primary immunodeficiency diseases was created by a committee convened by the …
window into the functioning of the immune system. In the late 1960s, observations on these
diseases, with their associated infections and genetics, bisected the immune system into
humoral immunity and cell-mediated immunity. These diseases also represent a challenge
in their diagnosis and treatment. Beginning in 1970, a unified nomenclature for the then-
known primary immunodeficiency diseases was created by a committee convened by the …