Acute renal failure and tubular cell loss as a result of ischemia constitute major challenges in
renal pathophysiology. Increasing evidence suggests important roles for bone marrow stem
cells in the regeneration of renal tissue after injury. This study investigated whether the
enhanced availability of hematopoietic stem cells, induced by stem cell factor and
granulocyte colony-stimulating factor, to the injured kidney provides an adequate strategy for
stem cell-based therapy to counteract renal ischemia/reperfusion injury. It is interesting that …