[HTML][HTML] Mechanism for fatty acid “sparing” effect on glucose-induced transcription: regulation of carbohydrate-responsive element-binding protein by AMP-activated …
T Kawaguchi, K Osatomi, H Yamashita… - Journal of Biological …, 2002 - ASBMB
Carbohydrate-responsive element-binding protein (ChREBP) is a new transcription factor
that binds to the carbohydrate-responsive element of the l-type pyruvate kinase gene (l-PK).
The aim of this study was to investigate the mechanism by which feeding high fat diets
results in decreased activity of ChREBP in the liver (Yamashita, H., Takenoshita, M., Sakurai,
M., Bruick, RK, Henzel, WJ, Shillinglaw, W., Arnot, D., and Uyeda, K.(2001) Proc. Natl. Acad.
Sci. USA 98, 9116–9121). We cloned the rat liver ChREBP gene for use throughout this …
that binds to the carbohydrate-responsive element of the l-type pyruvate kinase gene (l-PK).
The aim of this study was to investigate the mechanism by which feeding high fat diets
results in decreased activity of ChREBP in the liver (Yamashita, H., Takenoshita, M., Sakurai,
M., Bruick, RK, Henzel, WJ, Shillinglaw, W., Arnot, D., and Uyeda, K.(2001) Proc. Natl. Acad.
Sci. USA 98, 9116–9121). We cloned the rat liver ChREBP gene for use throughout this …