We recently reported that neuropeptide Y (NPY) protein levels and cAMP responsive
element binding (CREB) protein phosphorylation are lower in amygdaloid structures during
ethanol withdrawal after chronic exposure. Furthermore, we reported that normalization of
CREB phosphorylation by infusing protein kinase A (PKA) activator into the central
amygdala prevents anxiety-like effects in rats during ethanol withdrawal. Here we
investigated whether normalization of CREB phosphorylation by infusing PKA activator (Sp …