NPY antagonizes behavioral consequences of stress through actions within the brain.
Behavioral anti-stress actions of NPY are noteworthy in that (1) their magnitude surpasses
that of other endogenous compounds;(2) they are produced across a wide range of animal
models, normally thought to reflect different aspects of emotionality. This suggests that NPY
acts with a high potency on a common core mechanism of emotionality and behavioral
stress responses. Behavioral studies in genetically modified animals support this …