Acoustic startle and fear-potentiated startle in alcohol-preferring (P) and-nonpreferring (NP) lines of rats
DL McKinzie, TJ Sajdyk, WJ McBride… - Pharmacology …, 2000 - Elsevier
The objective of the present study was to determine whether alcohol-preferring P and-
nonpreferring NP rats differ in their acoustic startle response and in fear-potentiated startle.
In Experiment 1, male P and NP rats were tested on the startle response to acoustic stimuli
ranging from 90–115 dB. Experiments 2 and 3 examined fear-potentiated startle and
extinction of the response. In Experiment 2, rats received two light foot shock training
sessions separated by 3–4 h. Testing consisted of ten acoustic startle (115 dB) and fear …
nonpreferring NP rats differ in their acoustic startle response and in fear-potentiated startle.
In Experiment 1, male P and NP rats were tested on the startle response to acoustic stimuli
ranging from 90–115 dB. Experiments 2 and 3 examined fear-potentiated startle and
extinction of the response. In Experiment 2, rats received two light foot shock training
sessions separated by 3–4 h. Testing consisted of ten acoustic startle (115 dB) and fear …