[HTML][HTML] The LIM-only protein DRAL/FHL2 interacts with and is a corepressor for the promyelocytic leukemia zinc finger protein
P McLoughlin, E Ehler, G Carlile, JD Licht… - Journal of Biological …, 2002 - ASBMB
Members of the four-and-a-half-LIM domain (FHL) protein family, which are expressed in a
tissue-and stage-specific manner, have been reported previously to function as
transcriptional coactivators. One of these is the p53-inducible protein DRAL/FHL2 (where
DRAL is down-regulated in rhabdomyosarcoma LIM domain protein). In this work, we
identified potential binding partners for DRAL/FHL2 using an inducible yeast two-hybrid
system. We present evidence of a functional interaction between the promyelocytic leukemia …
tissue-and stage-specific manner, have been reported previously to function as
transcriptional coactivators. One of these is the p53-inducible protein DRAL/FHL2 (where
DRAL is down-regulated in rhabdomyosarcoma LIM domain protein). In this work, we
identified potential binding partners for DRAL/FHL2 using an inducible yeast two-hybrid
system. We present evidence of a functional interaction between the promyelocytic leukemia …