Copper, iron and zinc in Alzheimer's disease senile plaques
MA Lovell, JD Robertson, WJ Teesdale… - Journal of the …, 1998 - Elsevier
Concentrations of copper (Cu), iron (Fe) and zinc (Zn) were measured in the rims and cores
of senile plaques (SP) and in the neuropil of the amygdala of nine Alzheimer's disease (AD)
patients and in the neuropil of the amygdala of five neurologically normal control subjects
using micro particle-induced X-ray emission (micro-PIXE). Comparison of SP rim and core
values revealed no significant differences between levels of Cu, Fe or Zn. Zinc and Fe in SP
rims and cores were significantly elevated in AD compared with AD neuropil (P< 0.05) …
of senile plaques (SP) and in the neuropil of the amygdala of nine Alzheimer's disease (AD)
patients and in the neuropil of the amygdala of five neurologically normal control subjects
using micro particle-induced X-ray emission (micro-PIXE). Comparison of SP rim and core
values revealed no significant differences between levels of Cu, Fe or Zn. Zinc and Fe in SP
rims and cores were significantly elevated in AD compared with AD neuropil (P< 0.05) …