[HTML][HTML] Bacterial penetration across the blood-brain barrier during the development of neonatal meningitis
SH Huang, MF Stins, KS Kim - Microbes and infection, 2000 - Elsevier
Bacterial pathogens may breach the blood-brain barrier (BBB) and invade the central
nervous system through paracellular and/or transcellular mechanisms. Transcellular
penetration, eg, transcytosis across the BBB has been demonstrated for Escherichia coli K1,
group B streptococcus, Listeria monocytogenes, Citrobacter freundii and Streptococcus
pneumonia strains. Genes contributing to invasion of brain microvascular endothelial cells
include E. coli K1 genes ompA, ibeA, ibeB, and yijP. Understanding the mechanisms of …
nervous system through paracellular and/or transcellular mechanisms. Transcellular
penetration, eg, transcytosis across the BBB has been demonstrated for Escherichia coli K1,
group B streptococcus, Listeria monocytogenes, Citrobacter freundii and Streptococcus
pneumonia strains. Genes contributing to invasion of brain microvascular endothelial cells
include E. coli K1 genes ompA, ibeA, ibeB, and yijP. Understanding the mechanisms of …