Two Restriction and Modification Systems in Staphylococcus aureus nctc8325
S Iordanescu, M Surdeanu - Microbiology, 1976 - microbiologyresearch.org
S Iordanescu, M Surdeanu
Microbiology, 1976•microbiologyresearch.orgThe presence of two distinct host specificities in Staphylococcus aureus strain nctc8325 was
revealed by the isolation of restriction-and modification-deficient mutants. The two host
specificity systems, designated S1 and S2, are both active on phage 80 μ α but are not
additive in their restricting activity. Restriction-deficient, modification-proficient mutants were
invariably affected in both restriction systems. The functional relationship between these two
systems is discussed.
revealed by the isolation of restriction-and modification-deficient mutants. The two host
specificity systems, designated S1 and S2, are both active on phage 80 μ α but are not
additive in their restricting activity. Restriction-deficient, modification-proficient mutants were
invariably affected in both restriction systems. The functional relationship between these two
systems is discussed.
Summary
The presence of two distinct host specificities in Staphylococcus aureus strain nctc8325 was revealed by the isolation of restriction- and modification-deficient mutants. The two host specificity systems, designated S1 and S2, are both active on phage 80μα but are not additive in their restricting activity. Restriction-deficient, modification-proficient mutants were invariably affected in both restriction systems. The functional relationship between these two systems is discussed.
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