[PDF][PDF] Clearing Tau Pathology with Aβ Immunotherapy—Reversible and Irreversible Stages Revealed
M Hutton, E McGowan - Neuron, 2004 - cell.com
M Hutton, E McGowan
Neuron, 2004•cell.comThe report by Oddo and colleagues in this issue of Neuron demonstrates for the first time
that clearance of amyloid also results in the removal of early-stage tau pathology in mice that
develop both amyloid plaques and neurofibrillary tangles (NFT), the two hallmark lesions of
Alzheimer's disease (AD). This result supports a primary role for Aβ in AD etiology.
that clearance of amyloid also results in the removal of early-stage tau pathology in mice that
develop both amyloid plaques and neurofibrillary tangles (NFT), the two hallmark lesions of
Alzheimer's disease (AD). This result supports a primary role for Aβ in AD etiology.
Abstract
The report by Oddo and colleagues in this issue of Neuron demonstrates for the first time that clearance of amyloid also results in the removal of early-stage tau pathology in mice that develop both amyloid plaques and neurofibrillary tangles (NFT), the two hallmark lesions of Alzheimer's disease (AD). This result supports a primary role for Aβ in AD etiology.
cell.com