Spinal nerve injury increases the percentage of cold-responsive DRG neurons
L Djouhri, D Wrigley, PD Thut, MS Gold - Neuroreport, 2004 - journals.lww.com
We tested the hypothesis that cold allodynia, observed following nerve injury reflects change
(s) in the cold responsiveness of sensory neurons. To test this hypothesis we assessed the
impact of the spinal nerve ligation (SNL) model of nerve injury on the responses of
cutaneous sensory neurons to cooling in vitro. Nerve injury induced a significant increase in
the incidence of cold responsive cutaneous neurons in uninjured but not injured ganglia.
Because an increase in the percentage of cold responsive neurons in uninjured ganglia …
(s) in the cold responsiveness of sensory neurons. To test this hypothesis we assessed the
impact of the spinal nerve ligation (SNL) model of nerve injury on the responses of
cutaneous sensory neurons to cooling in vitro. Nerve injury induced a significant increase in
the incidence of cold responsive cutaneous neurons in uninjured but not injured ganglia.
Because an increase in the percentage of cold responsive neurons in uninjured ganglia …