Expression of vascular endothelial growth factor receptor-3 (VEGFR-3) on monocytic bone marrow-derived cells in the conjunctiva

P Hamrah, L Chen, C Cursiefen, Q Zhang… - Experimental eye …, 2004 - Elsevier
Vascular endothelial growth factor-3 (VEGFR-3), also known as Fms-like tyrosine kinase
receptor 4 (FLT-4), was thought to be expressed exclusively on the lymphatic endothelium,
high endothelial venules, and rarely on vascular endothelium. It plays a critical role in the
development of lymphatics and cancer metastasis. Very recently, however, VEGFR-3
expression has been identified on dendritic cells (DCs) in the inflamed cornea, and related
to the trafficking of these cells to lymphoid organs. The current study was performed to …