[HTML][HTML] Native and modified low density lipoproteins increase the functional expression of the macrophage class B scavenger receptor, CD36
J Han, DP Hajjar, M Febbraio, AC Nicholson - Journal of Biological …, 1997 - ASBMB
The uptake of oxidized low density lipoprotein (OxLDL) by macrophages is a key event
implicated in the initiation and development of atherosclerotic lesions. Two macrophage
surface receptors, CD36 (a class B scavenger receptor) and the macrophage scavenger
receptor (a class A scavenger receptor), have been identified as the major receptors that
bind and internalize OxLDL. Expression of CD36 in monocyte/macrophages in tissue culture
is dependent both on the differentiation state as well as exposure to soluble mediators …
implicated in the initiation and development of atherosclerotic lesions. Two macrophage
surface receptors, CD36 (a class B scavenger receptor) and the macrophage scavenger
receptor (a class A scavenger receptor), have been identified as the major receptors that
bind and internalize OxLDL. Expression of CD36 in monocyte/macrophages in tissue culture
is dependent both on the differentiation state as well as exposure to soluble mediators …