Prolonged acute exposure to 0.16 ppm ozone induces eosinophilic airway inflammation in asthmatic subjects with allergies
DB Peden, B Boehlecke, D Horstman… - Journal of allergy and …, 1997 - Elsevier
Background: Increased ambient ozone levels have been associated with increased asthma
morbidity in epidemiologic studies. Given that asthma is characterized by airway
inflammation and increased sensitivity to airway irritants, it has been suggested that
asthmatic subjects may be particularly sensitive to the effect of ozone. Objective: The
objective of this study was to determine whether exposure to 0.16 ppm ozone induces
eosinophilic inflammation in the lower airways of asthmatic subjects. Methods: Eight …
morbidity in epidemiologic studies. Given that asthma is characterized by airway
inflammation and increased sensitivity to airway irritants, it has been suggested that
asthmatic subjects may be particularly sensitive to the effect of ozone. Objective: The
objective of this study was to determine whether exposure to 0.16 ppm ozone induces
eosinophilic inflammation in the lower airways of asthmatic subjects. Methods: Eight …