[HTML][HTML] Paracrine and autocrine functions of neuronal vascular endothelial growth factor (VEGF) in the central nervous system
OO Ogunshola, A Antic, MJ Donoghue, SY Fan… - Journal of Biological …, 2002 - ASBMB
Recent data have demonstrated that vascular endothelial growth factor (VEGF) is expressed
by subsets of neurons, coincident with angiogenesis within the developing cerebral cortex.
Here we investigate the characteristics of VEGF expression by neurons and test the
hypothesis that VEGF may serve both paracrine and autocrine functions in the developing
central nervous system. To begin to address these questions, we assayed expression of
VEGF and one of its potential receptors, Flk-1 (VEGFR-2), in the embryonic mouse forebrain …
by subsets of neurons, coincident with angiogenesis within the developing cerebral cortex.
Here we investigate the characteristics of VEGF expression by neurons and test the
hypothesis that VEGF may serve both paracrine and autocrine functions in the developing
central nervous system. To begin to address these questions, we assayed expression of
VEGF and one of its potential receptors, Flk-1 (VEGFR-2), in the embryonic mouse forebrain …