[CITATION][C] Erythromycin-induced long QT syndrome: concordance with quinidine and underlying cellular electrophysiologic mechanism
S Nattel, S Ranger, M Talajic, R Lemery… - The American journal of …, 1990 - Elsevier
The drug-induced long QT syndrome is a specific form of tachyarrhythmia that may
complicate therapy with a range of compounds [2, 3]. This syndrome consists of a marked
QT-interval prolongation on the electrocardiogram, often accompanied by an exaggerated U
wave, associated with polymorphic ventricular tachycardias of a characteristic undulating
morphology called “torsades de pointes”[4]. These tachyarrhythmias are usually self-
terminating [l] but frequently result in syncope, and they can degenerate to ventricular …
complicate therapy with a range of compounds [2, 3]. This syndrome consists of a marked
QT-interval prolongation on the electrocardiogram, often accompanied by an exaggerated U
wave, associated with polymorphic ventricular tachycardias of a characteristic undulating
morphology called “torsades de pointes”[4]. These tachyarrhythmias are usually self-
terminating [l] but frequently result in syncope, and they can degenerate to ventricular …