Female gender as a risk factor for torsades de pointes associated with cardiovascular drugs

RR Makkar, BS Fromm, RT Steinman, MD Meissner… - Jama, 1993 - jamanetwork.com
Objective.—To test the hypothesis that female prevalence is greater than expected among
reported cases of torsades de pointes associated with cardiovascular drugs that prolong
cardiac repolarization. Data Sources.—A MEDLINE search of the English-language
literature for the period of 1980 through 1992, using the termstorsade de pointes,
polymorphic ventricular tachycardia, atypical ventricular tachycardia, proarrhythmia,
anddrug-induced ventricular tachycardia, supplemented by pertinent references (dating …